Benfluorex hydrochloride ( Benfluorex HCl; Benfluorex hydrochloride; Lipophoral; Mediator; JP 992 )

Catalog No. M13679 CAS No. 23642-66-2

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Product Name

Benfluorex hydrochloride
Note

Research use only, not for human use.
Brief Description

Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine.
Description

Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. On 18 December 2009, the European Medicines Agency (EMEA) recommended the withdrawal of all medicines containing benfluorex in the European Union, because their risks, particularly the risk of heart valve disease (fenfluramine-like cardiovascular side-effects), are greater than their benefits.
Synonyms

Benfluorex HCl; Benfluorex hydrochloride; Lipophoral; Mediator; JP 992
Pathway

Others
Target

Other Targets
Recptor

HNF4α
Research Area

Cardiovascular Disease
Indication

——

CAS Number

23642-66-2
Formula Weight

387.82
Molecular Formula

C19H21ClF3NO2
Purity

>98%(HPLC)
Solubility

Soluble in DMSO
SMILES

O=C(OCCNC(C)CC1=CC=CC(C(F)(F)F)=C1)C2=CC=CC=C2.[H]Cl
Chemical Name

2-((1-(3-(trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride

1.Lee SH, et al. ACS Chem Biol. 2013 Aug 16;8(8):1730-6.

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